吡罗昔康Piroxicam：NOXA20核心成分解析

　　吡罗昔康（Piroxicam）是NOXA20的核心成分，属于非甾体抗炎药，通过抑制环氧合酶减轻炎症。

▲吡罗昔康胶囊

　　【成分解析】吡罗昔康（Piroxicam）是一种昔康类非甾体抗炎药（NSAID），通过抑制环氧合酶（COX-1和COX-2），减少前列腺素合成，从而发挥抗炎、镇痛和解热作用。

　　　【药代动力学】口服后吸收迅速，2-4小时达血药峰值。半衰期约50小时，每日一次给药即可维持稳定血药浓度。

　　【作用机制】抑制炎症部位的前列腺素合成，减轻关节红、肿、热、痛。

　　【适用症状】痛风急性发作、类风湿关节炎、骨关节炎、强直性脊柱炎、肌肉疼痛。

English Translation

Piroxicam is the core ingredient of NOXA20. It is an oxicam-class non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) to reduce prostaglandin synthesis, providing anti-inflammatory, analgesic, and antipyretic effects.

Pharmacokinetics: Rapidly absorbed after oral administration, peak plasma concentration in 2-4 hours. Half-life about 50 hours, allowing once-daily dosing.

Mechanism: Inhibits prostaglandin synthesis at inflamed sites, reducing joint redness, swelling, heat, and pain.

Indications: Acute gout attacks, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and muscle pain.

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